YAP1 antibody (AA 350-504)

Catalog No. ABIN5704560

This anti-YAP1 antibody is a Rabbit Polyclonal antibody detecting YAP1 in WB, ELISA, IHC, IF, FACS and IP. Suitable for Human, Mouse and Zebrafish (Danio rerio).

Quick Overview for YAP1 antibody (AA 350-504) (ABIN5704560)

Target: YAP1 (Yes-Associated Protein 1 (YAP1))

Reactivity: Human, Mouse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YAP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunoprecipitation (IP)

Product Details anti-YAP1 Antibody

Binding Specificity: AA 350-504

Purpose: YAP1 antibody

Immunogen:

Immunogen sequence: 350-504aa

Immunogen: Yes-associated protein 1, 65kDa

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:5000,IHC:1:50-1:200,IF:1:20-1:200,IP:1:200-1:2000

Comment:

HeLa cells were subjected to SDS PAGE followed by western blot with FNab09559( YAP1 Antibody) at dilution of 1:1000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for YAP1

Target: YAP1 (Yes-Associated Protein 1 (YAP1))

Alternative Name: YAP1

Background:

Synonyms: Transcriptional coactivator YAP1 (Yes-associated protein 1)|Protein yorkie homolog|Yes-associated protein YAP65 homolog|YAP1|YAP65

Background: This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: 108kDa

Gene ID: 10413

UniProt: P46937

Pathways: MAPK Signaling, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha